Davies NG, Abbott S, Barnard RC, Jarvis CI, Kucharski AJ, Munday JD, Pearson CAB, Russell TW, Tully DC, Washburne AD, Wenseleers T, Gimma A, Waites W, Wong KLM, van Zandvoort K, Silverman JD, CMMID COVID-19 Working Group. In these situations, use the following HCPCS codes to bill for casirivimab and imdevimab: The September 16, 2021, revised EUA for bamlanivimab and etesevimab allows for its use for PEP in certain adult and pediatric patients. Monoclonal antibody therapy has been suggested as an option for preventing progression to severe COVID-19 infection in high-risk individuals and reducing hospitalizations. Effective for IV injection services furnished on or after February 11, 2022 (such as the administration of bebtelovimab), the Medicare payment rate for administering these COVID-19 monoclonal antibody products, authorized or approved by the FDA, is approximately $350.50. This rate reflects updated information about the costs involved in furnishing these complex products in a patients home. Evusheld therapy is made up of 1 injection of tixagevimab and 1 injection of cilgavimab, given separately into your muscle, one right after the other. While individuals of all ages are at risk of contracting COVID-19 and developing severe disease, several risk factors have been identified that place patients at higher risk for morbidity and mortality. The FDA approvals and EUAs for COVID-19 monoclonal antibody products contain specific requirements for administration that are considerably more complex than for other services that use roster billing. For more information about the limits of authorized use for these monoclonal antibody therapies, including information about viral variants and antiviral resistance, review the following: The virus that causes COVID-19 (SARS-CoV-2) is constantly changing, and CDC expects new viral variants to continue to emerge. Yesudhas D, Srivastava A, Gromiha MM. Healthcare providers should also be aware of the resistance of certain variants of the SARS-CoV-2 virus. Bebtelovimab (EUA issued February 11, 2022, latest update October 27, 2022). The antibodies . Hospitals, urgent care centers and even private doctors are authorized to dispense them. The interprofessional healthcare team is also responsible for educating the patient on infection control measures. Casirivimab/imdevimab - Wikipedia [20], Sotrovimab, also called VIR-7831, is the only monoclonal antibody currently authorized for use. Vaccines prevent progression for a larger part of the population. bruising of the skin. It works by stopping SARS-CoV-2 from spreading in the body. Doessegger L, Banholzer ML. The emergency use authorization(EUA) for sotrovimab is for use in non-hospitalized patients 12 years or older, weighing more than 40 kg, with mildor moderate symptoms, who have one or more risk factors for progression to severe disease. They Shunned Covid Vaccines but Embraced Antibody Treatment Monoclonal antibodies are laboratory-made "substitute antibodies" that can help the immune system recognize and respond more effectively to COVID-19, according to the U.S. Food and Drug. On December 23, 2022, the. If you administer COVID-19 monoclonal antibodies to Medicare patients in traditional health care locations (for example, a hospital outpatient infusion clinic or freestanding infusion clinic), continue to bill HCPCS codes M0240, M0243, M0245, M0247, or M0222, as applicable. By binding to the viral spike protein's receptor-binding domain(RBD), these antibodies competitively inhibit ACE2 receptor binding and prevent viral entry into the cell. If your hospice patients Medicare Advantage plan participates in the Hospice Benefit Component of the Value-Based Insurance Design (VBID) Model, submit claims for administering COVID-19 monoclonal antibody products to the Medicare Advantage Plan. Nonetheless, monoclonal antibodies appear to be a promising option in the treatment of COVID-19 and have the potential to prevent hospitalizations and mortality. The new rate reflects updated information about the costs involved in administering these types of monoclonal antibody products for different types of providers and suppliers and the resources necessary to ensure providers administer the products safely and appropriately. They are considered a promising approach in managing nonhospitalized patients with mild to moderate COVID-19 who are at high risk of developing severe illness. ( See Limitations of Authorized Use. This study showed a high prevalence of transient COVID-19 vaccine-related side-effects after primary and booster doses. Monoclonal antibody therapy is a way of treating COVID-19 for people who have tested positive, have had mild symptoms for seven days or less, and are at high risk for developing more serious symptoms. Monoclonal Antibody Side Effects | American Cancer Society There was 1 total death in this study that received a placebo. Adverse Reactions An EUA for sotrovimab for treatment of COVID-19. http://creativecommons.org/licenses/by-nc-nd/4.0/. For details about specific variants and monoclonal antibody resistance, review the Antiviral Resistance information in each of the Fact Sheets listed above. Starting August 15, 2022, bebtelovimab will be commercially available. Per the CDC, there have been over 48 million cases in the United States alone, and greater than 777,000 deaths reported due to Covid-19 infection. Effective for services furnished on or after May 6, 2021, the Medicare payment rate for administering COVID-19 monoclonal antibody products through infusion in a patients home or residence is approximately $750. Patients must be observed for at least one hour after receiving a monoclonal antibody to ensure patient safety. .gov Review the Antiviral Resistance information in the Fact Sheet for each monoclonal antibody therapy authorized under anemergency use authorization (EUA)for details regarding specific variants and resistance. Monoclonal antibodies are lab-made proteins that mimic the immune system's ability to fight off viruses and other harmful pathogens, per the FDA. In December of 2019, an outbreak of severerespiratory infections was noticed in Wuhan, China. Providers and suppliers should use Q0245 and M0245 or M0246 to bill for administering bamlanivimab and etesevimab for PEP. Antibody Cocktail Reduces Chance of Developing COVID - Medscape This means your patients don't pay a copay/coinsurance or deductible: Sign up to get the latest information about your choice of CMS topics. Dupixent (Dupilumab) Subcutaneous: Uses, Side Effects, Dosage Monoclonal antibodies targeting the spike protein of the SARS-CoV-2 have yielded positive in vitro results. Healthcare providers must be able to recognize patients at risk for progression to severe disease who would benefit from monoclonal antibody infusion and recognize which patients must be hospitalized for severe infection. There are several variants of concern that have been identified, such as the Alpha variant (B1.1.7 lineage, UK origin), Beta variant (B.1351 lineage, South African origin), Gamma variant (P.1/B.1.1.28.1 lineage, Brazilian origin), Delta variant (B1.617.2 lineage, Indian origin). The most commonly reported side effect was diarrhea (1%).[22]. [15]The virus gains entry into the cell by binding its spike protein to the angiotensin-converting enzyme 2 receptors on host cells. Medicare doesnt pay for the COVID-19 monoclonal antibody products that providers get for free, including: The government wont purchase the following products and make them available for free: CMS set the payment ratefor COVID-19 monoclonal antibody products the same way we set the payment rate for COVID-19 vaccines. Hypersensitivity, including infusion-related and . What to Know About Monoclonal Antibodies for COVID-19 - WebMD Get the. See theEUAfor more information. As demonstrated above, monoclonal antibody therapy used in the treatment of outpatient COVID-19 in patients at risk for developing severe disease has the potential to decrease hospitalizations and mortality. [2][3][4]At this time, however, there is minimal data that suggests these therapies improve outcomes. https:// Beaver CC, Magnan MA. As a result, Medicare hasnt created a separate HCPCS code for billing for the higher Medicare payment amount for administering tocilizumab in the home. Management and preparedness for infusion and hypersensitivity reactions. Learn more about treatment guidelines and recommendations for using monoclonal antibody therapies. StatPearls Publishing, Treasure Island (FL). Get the most current list of billing codes, payment allowances, and effective dates for currently authorized monoclonal antibody products.More Information about Payment for Infusion & IV Injection Smith Park in Pembroke Pines. There are specific conditions people need to meet in order to receive the medication. The word "monoclonal" refers to the fact that the antibodies created in the laboratory are clones. What to Know About Monoclonal Antibodies - CNET Monoclonal antibodies prevent progression to severe disease, are not equally effective across variants, and are associated with minimal and self-limited reactions. Evusheld to prevent Covid-19: There won't be nearly enough for - CNN There are now 21 clinics around the state, including two in South Florida in Broward and Miami . A brief review of monoclonal antibody technology and its representative applications in immunoassays. Continue to bill for administering either type of product. The July 30, 2021, revised EUA for casirivimab and imdevimab allows for its use for post-exposure prophylaxis (PEP) for certain patients who have been exposed to (or are at high risk of exposure to) a person with COVID-19. At high risk of dying from the virus, Barron remains a virtual prisoner in her . These rates dont apply if Medicare pays you for preventive vaccines and their administration at reasonable cost (for example, FQHCs, RHCs, and hospital-based renal dialysis facilities). Risk factors for worsening infection include chronic medical problems like diabetes, a weakened immune system, and age greater than 65. This rate applies to all providers and suppliers not paid reasonable cost for furnishing these products. Tardif JC, Bouabdallaoui N, L'Allier PL, Gaudet D, Shah B, Pillinger MH, Lopez-Sendon J, da Luz P, Verret L, Audet S, Dupuis J, Denault A, Pelletier M, Tessier PA, Samson S, Fortin D, Tardif JD, Busseuil D, Goulet E, Lacoste C, Dubois A, Joshi AY, Waters DD, Hsue P, Lepor NE, Lesage F, Sainturet N, Roy-Clavel E, Bassevitch Z, Orfanos A, Stamatescu G, Grgoire JC, Busque L, Lavalle C, Htu PO, Paquette JS, Deftereos SG, Levesque S, Cossette M, Nozza A, Chabot-Blanchet M, Dub MP, Guertin MC, Boivin G., COLCORONA Investigators. Monoclonal antibodies, . Benefits And Risks Of Administering Monoclonal Antibody Therapy For The pharmacy staff should be aware of the proper storage and handling of the medications. COVID-19 Treatments: What We Know So Far > News > Yale Medicine The U.S. Food and Drug Administration has authorized treatments that have already been taken by millions of people, reducing their COVID-19 symptoms and keeping many of them out of the hospital. The effects also could lead to the development of new conditions, such as diabetes or a heart or nervous . Lenz HJ. They are accessible on an outpatient basis, via a single infusion or four injections. There are now Regeneron monoclonal antibody treatment clinics in Jacksonville, Ormond . Sotrovimab contains a mutation in its fragment crystallizable(Fc) region that gains an extended half-life and enhances distribution to the lungs. Monoclonal antibody therapy is indicated for use in non-hospitalized patients with mild to moderate disease who have risk factors for progression to severe disease. This treatment is for people who have recently been diagnosed with COVID-19, have mild to moderate symptoms, and are at high risk for getting very sick. The safety and side effects of monoclonal antibodies - PubMed Possible side effects of COVID-19 monoclonal antibodies can include: nausea or vomiting diarrhea fever or chills drop in blood pressure headache or dizziness muscle pains or aches itching. Get the most current list of billing codes, payment allowances, and effective dates for currently authorized monoclonal antibody products. The name of the provider who ordered or decided to administer the infusion or injection, even in cases where providers use roster billing to submit claims for these services, Rural Health Clinics (RHCs) and Federally Qualified Health Centers (FQHCs), Through the end of the calendar year in which the EUA declaration ends for monoclonal antibody products used for post-exposure prophylaxis or for treatment of COVID-19, Permanently for covered monoclonal antibody products used as pre-exposure prophylaxis for prevention of COVID-19. Dolgin E. 'Super-antibodies' could curb COVID-19 and help avert future pandemics. CMS created HCPCS code J0248 for VEKLURY, effective December 23, 2021. Typical side effects include pain at the injection site, fever, fatigue, headache, muscle pain, chills and diarrhoea. Monoclonal antibodies, such as bamlanivimab and etesevimab, may be associated with worse clinical outcomes when administered to hospitalized patients with COVID-19 requiring high-flow oxygen or mechanical ventilation. For example, Medicare will pay 95% of AWP for COVID-19 vaccines provided in the physician office setting, and pay hospital outpatient departments at reasonable cost for COVID-19 vaccines. We geographically adjust the rate based on where you furnish the service. Side effects: Nausea is the most common side effect. In clinical trials, mAb (Casirivimab/Imdevimab) treatment reduced the risk of hospitalization by 50% in patients with mild to moderate COVID-19. Tigecycline (TGC), a third-generation tetracycline, is characterized by a more potent and broad antibacterial activity, and the ability to overcome different mechanisms of tetracycline resistance. [21], The major benefits derived from the monoclonal antibody therapies appear to be a reduction in viral load, hospitalizations, and death. Per the fact sheet issued by the FDA for sotrovimab, the dosage authorized is 500 mg of sotrovimab as a single IV infusion administered over 30 minutes. Inpatient locations, such as inpatient hospitals, inpatient psychiatric hospitals, long-term care hospitals, and inpatient rehabilitation hospitals, would never qualify as the home or residence for purposes of HCPCS codes M0241, M0244, M0246, M0248, or M0223. The highly contagious nature of the virus and its high potential for morbidity and mortality has overwhelmed hospital systems worldwide with hospitalizations and deaths. Monoclonal antibodies boost the immune system after you are already sick, speeding up your immune response to prevent COVID-19 from getting worse. These are not all the possible side effects of this medication, which has not been given to a lot of people. The safety and side effects of monoclonal antibodies. Researchers founda reduction in combined hospitalizations and death with 1% in the treatment group and 7% in the placebo group. COVID-19 outbreak: history, mechanism, transmission, structural studies and therapeutics. COVID-19: Long-term effects - Mayo Clinic - Mayo Clinic - Mayo Clinic Learn About Evusheld, the Monoclonal Antibody to Prevent COVID-19 in In: StatPearls [Internet]. Monoclonal antibodies are one such treatment that may . Under the terms of the FDA approval and EUA, health care providers can only administer ACTEMRA (tocilizumab) to hospitalized patients in limited clinical situations. Serious and unexpected side effects may happen. Scientists have wondered if infection with SARS-CoV-2 could also result in the production of autoantibodies in people who didn't have them before they got sick. As a result, CMS issued a new product code for REGEN-COV (Q0244) and updated the descriptors for the existing administration codes (M0243/M0244). This likely will bring more attention to this treatment, which has proven to cut . COVID-19 Therapeutics: Use, Mechanism of Action, and Toxicity (Vaccines There may not be data from patients, but lab studies strongly suggest the treatments will not help omicron-infected people. Omicron's resistance to the two leading monoclonal antibody medicines has upended the treatment playbook for Covid-19 in recent weeks. Getting a vaccine is safer than getting COVID-19, and vaccination against COVID-19 is recommended for everyone 5 years of age and older. Monoclonal Antibodies: Definition & How Treatment Works - Cleveland Clinic Effective for services furnished on or after December 8, 2021, the Medicare payment rate for administering COVID-19 monoclonal antibody products through intramuscular injection for pre-exposure prophylaxis (such as tixagevimab co-packaged with cilgavimab, administered as 2 separate consecutive intramuscular injections), in select patient populations, is approximately $150.50. On November 30, 2022, the, The patient has a positive COVID-19 test result, The patient is at high risk for progressing to severe COVID-19, hospitalization, or both, Immediate access to medications to treat a severe infusion reaction, such as anaphylaxis, The ability to activate the emergency medical system (EMS), Refer to information from your state and local health authorities, REGEN-COV (casirivimab and imdevimab, administered together) (not currently authorized in any U.S region), Bamlanivimab and etesevimab, administered together(not currently authorized in any U.S region), Sotrovimab(not currently authorized in any U.S. region), Freestanding and hospital-based infusion centers, Entities with whom nursing homes contract to administer products, M0243 or M0244 when billing for the administration of the initial dose in a health care setting or the home, M0240 or M0241 when billing for the administration of any subsequent repeat doses in a health care setting or the home, M0245 when billing to administer in a health care setting, M0246 when billing to administer in the home or residence, Consistent with existing payment methodologies for the care setting where you provide the treatment, Casirivimab and imdevimab, to be administered together, Bamlanivimab and etesevimab, to be administered together, Tixagevimab co-packaged with cilgavimab, administered as 2 separate consecutive intramuscular injections, Bebtelovimab (if you got the product for free). lock Evusheld is the only non-vaccine with emergency use authorization (EUA) from the FDA to prevent infection from COVID-19 before you're exposed to the virus. Ju B, Zhang Q, Ge J, Wang R, Sun J, Ge X, Yu J, Shan S, Zhou B, Song S, Tang X, Yu J, Lan J, Yuan J, Wang H, Zhao J, Zhang S, Wang Y, Shi X, Liu L, Zhao J, Wang X, Zhang Z, Zhang L. Human neutralizing antibodies elicited by SARS-CoV-2 infection. For many providers and suppliers, we also geographically adjust this rate based on where you furnish the service. The Food and Drug Administration authorized the first injectable monoclonal antibody cocktail for long-term prevention of Covid-19 among people with weakened immune systems before they have. But Regeneron Pharmaceuticals, maker of the only authorized, free monoclonal . Common side effects of monoclonal antibodies include: Allergic reactions Chills Weakness Diarrhea Nausea Vomiting Rash Itching High blood glucose levels Cough Constipation Other side effects of monoclonal antibodies include: Shortness of breath Peripheral edema Headache Fever Muscle aches and pain Decreased appetite Increased triglyceride levels Effective for services furnished on or after February 11, 2022, the Medicare payment rate for administering COVID-19 monoclonal antibody products through IV injection (such as bebtelovimab) in a patients home or residence is approximately $550.50. For example, if you administer 200mg of tocilizumab in 1 infusion, you should add 200 as the number of units on the claim. Although the Food and Drug Administration gave these treatments . Although the Food and Drug Administration gave these treatments like Regeneron emergency use authorization in 2020, the criteria for who is eligible to receive them has expanded. More Information about Payment for Infusion & IV Injection at Home. Intramuscular Injection Of Monoclonal Antibodies Simplifies Covid Treatment It isn't clear how long these effects might last. Healthcare providers and scientists are investigating . Healthcare providers must also educate the patient on symptoms that mark progression to severe disease and prompt the patient to return for reevaluation. All adverse events related to monoclonal antibody treatment must be reported according to the instructions found in the fact sheets released by the FDA. Side effects may occur from mAbs treatment including rash, diarrhea, nausea, dizziness and pruritis (itchy skin). See the, Fact Sheet for Health Care Providers EUA of Bebtelovimab, EVUSHELD (tixagevimab co-packaged with cilgavimab), administered as 2 separate consecutive intramuscular injection, (not currently authorized in any U.S. region), Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 600 mg, Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), includes injection and post administration monitoring, Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), includes injection and post administration monitoring in the home or residence; this includes a beneficiarys home that has been made provider-based to the hospital during the covid-19 public health emergency, Intravenous injection, bebtelovimab, includes injection and post administration monitoring, Intravenous injection, bebtelovimab, includes injection and post administration monitoring in the home or residence; this includes a beneficiarys home that has been made provider-based, CMS will pay you for monoclonal antibody products usedfor post-exposure prophylaxis or for treatment of COVID-19 as biological products paid under, When you administermonoclonal antibodies for post-exposure prophylaxis or for treatment of COVID-19, CMS will pay you under the applicable payment system, using the appropriate coding and payment rates, similar to the way we pay for administering other complex biological products, CMS will continue to pay for covered monoclonal antibody products and their administration when used as pre-exposure prophylaxis for prevention of COVID-19 under the Part B vaccine benefit even after the EUA declaration ends, The FDA approval and EUA for ACTEMRA also allows for 2 infusions for the same patient in limited situations. The antibodies themselves are proteins, so giving them can sometimes cause something like an allergic reaction. pain. Effective February 11, 2022, Medicare established separate coding and payment for administering COVID-19 monoclonal antibody products through IV injection in a patients home or residence. This book is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) A benefit of casirivimab and imdevimab treatment has not been shown in people hospitalized due to COVID19. The chances of any of these side effects occurring after vaccination differ according to the specific vaccine. Monoclonal antibodies are given intravenously (injected into a vein). No dosing adjustments are recommended for patients based on renal impairment, pregnancy, or lactation status. Gao Y, Huang X, Zhu Y, Lv Z. Infusion-related reactions typically present after 30to 60 minutes after initiating the infusion. We allow Medicare-enrolled immunizers including, but not limited to, pharmacies working with the U.S., infusion centers, and home health agencies to bill directly and get direct payment from the Medicare Program for vaccinating Medicare SNF residents. 7500 Security Boulevard, Baltimore, MD 21244, An official website of the United States government, ACTEMRA (tocilizumab) (EUA issued June, 24 2021, latest update December 21, 2022). swelling. However, these side-effects waned within 48 h. Pain at the injection site was the most common local side-effect, while fatigue, fever, headache and muscle pain were frequently repo The cause wasdemonstrated to be anovel coronavirus, called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Discuss with your healthcare provider any symptoms you are experiencing after treatment. This activity outlines the indications, actions, contraindications, and adverse events for monoclonal antibody therapy as a valuable treatment for outpatient COVID-19 infections. Hansel TT, Kropshofer H, Singer T, Mitchell JA, George AJ. Tixagevimab and cilgavimab are long-acting monoclonal antibodies meant to directly target the spike protein of SARS-CoV-2 and block the virus' attachment to and invasion of your cells. CMS geographically adjusts the rate based on where you furnish the service. Monoclonal antibodies are proteins developed in a lab in order to fight off infections that our bodies aren't familiar with, like COVID-19. Sotrovimab is not authorized for subcutaneous administration. Some people report mild side effects, like headache or stomach upset/nausea. Bamlan and etesev infus home, Note: This product isnt currently authorized[6], Long descriptor: Injection, sotrovimab, 500 mg, Long Descriptor: Intravenous infusion, sotrovimab, includes infusion and post administration monitoring, Long Descriptor: Intravenous infusion, sotrovimab, includes infusion and post administration monitoring in the home or residence; this includes a beneficiarys home that has been made provider-based to the hospital during the COVID-19 public health emergency, Short Descriptor: Sotrovimab inf, home admin, Genentechs Antibody ACTEMRA (tocilizumab), Long descriptor: Injection, tocilizumab, for hospitalized adults and pediatric patients (2 years of age and older) with covid-19 who are receiving systemic corticosteroids and require supplemental oxygen, non-invasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation (ECMO) only, 1 mg, Short descriptor: Tocilizumab for COVID-19, Long Descriptor: Intravenous infusion, tocilizumab, for hospitalized adults and pediatric patients (2 years of age and older) with covid-19 who are receiving systemic corticosteroids and require supplemental oxygen, non-invasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation (ECMO) only, includes infusion and post administration monitoring, first dose, Short Descriptor: Adm Tocilizu COVID-19 1st, Long descriptor: Intravenous infusion, tocilizumab, for hospitalized adults and pediatric patients (2 years of age and older) with covid-19 who are receiving systemic corticosteroids and require supplemental oxygen, non-invasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation (ECMO) only, includes infusion and post administration monitoring, second dose, Short descriptor: Adm Tocilizu COVID-19 2nd, AstraZenecas Antibody EVUSHELD (tixagevimab and Cilgavimab)Note: This product isnt currently authorized[8], Long descriptor: Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 300 mg, Long descriptor: Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), includes injection and post administration monitoring, Long descriptor: Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), includes injection and post administration monitoring in the home or residence; this includes a beneficiarys home that has been made provider-based to the hospital during the covid-19 public health emergency, Short descriptor: Tixagev and cilgav inj hm, Long Descriptor:Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 600 mg, Short Descriptor:Tixagev and cilgav, 600mg, Long descriptor:Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), includes injection and post administration monitoring, Long descriptor:Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), includes injection and post administration monitoring in the home or residence; this includes a beneficiarys home that has been made provider-based to the hospital during the covid-19 public health emergency, Short descriptor:Tixagev and cilgav inj hm, Eli Lilly and Companys Antibody Bebtelovimab (PDF), Note: This product isnt currently authorized[7], Long descriptor:Injection, bebtelovimab, 175 mg, Long Descriptor:Intravenous injection, bebtelovimab, includes injection and post administration monitoring, Long Descriptor:Intravenous injection, bebtelovimab, includes injection and post administration monitoring in the home or residence; this includes a beneficiarys home that has been made provider-basedto the hospital during the covid-19 public health emergency, Short Descriptor: Bebtelovimab injection home.
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